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U.S. FULL PRESCRIBING INFORMATION, including Boxed WARNINGS, and Medication Guide.

Antidepressants may increase suicidal thoughts or behaviors in some children, teenagers, and young adults, especially within the first few months of treatment or when the dose is changed. Depression and other serious mental illnesses are themselves associated with an increase in the risk of suicide. Patients on antidepressants and their families or caregivers should watch for new or worsening depression symptoms, unusual changes in behavior, or thoughts of suicide. Such symptoms should be reported to the patient’s healthcare provider right away, especially if they are severe or occur suddenly. ABILIFY®(aripiprazole) is not approved for use in pediatric patients with depression. See More Safety Information

INDICATION: ABILIFY (aripiprazole) is used for the treatment of manic and mixed episodes associated with bipolar I disorder in adults and in pediatric patients 10 to 17 years of age. It can be used either by itself or as an add-on treatment to lithium or valproate.

The individuals who appear on this page are for illustrative
purposes only. Any person depicted here is a model and not an
actual patient unless otherwise noted.

Understanding Bipolar I Disorder

Bipolar I disorder is a serious mental illness
marked by extreme changes in mood, thinking,
and behavior—all of which can affect personal relationships with friends and family.


There are no lab tests that can detect bipolar I disorder. A doctor must take a thorough history of your child and your family. He or she will ask about your child's moods, behavior, sleep habits, and other factors. It is important to be honest about all your child's symptoms, such as feeling unusually happy, energetic, or talking fast. And because bipolar I disorder can be mistaken for other conditions, the doctor may also use tests to see if your child's symptoms could be caused by another illness.

There have been recent changes in the definition of symptoms for bipolar I disorder. Please see your child's healthcare provider for more information about these changes.


While the specific cause of bipolar I disorder is not yet known, it’s thought to be caused by an imbalance of chemicals found in the brain. Some research suggests that bipolar I disorder runs in families. Learn more

Challenges For Your Child

Bipolar I disorder can take a toll on children’s ability to function in different areas, such as at home, at school, and in social situations. They may have trouble connecting with family members or peers. They may have mood swings at inappropriate times, causing others to react in a certain way. They may also have difficulty concentrating and remembering things. In general, they probably feel misunderstood.

It's important to try and relate to your child and understand the challenges he or she may be facing. That way, you'll learn how to handle certain situations better, while helping your child to cope better with things and people.

Substance abuse and suicide are serious risks, which is why accurate diagnosis is so important for children and teens who may have bipolar I disorder. With proper treatment, bipolar I disorder symptoms can be managed.

Important Safety Information About Allergic Reactions: Patients should not use ABILIFY (aripiprazole) if they are allergic to aripiprazole or any of the ingredients in ABILIFY. Allergic reactions have ranged from rash, hives and itching to anaphylaxis, which may include difficulty breathing, tightness in the chest, and swelling of the mouth, face, lips, or tongue.

See More Safety Information
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  • Symptoms of Bipolar I Disorder

    Learn more about the symptoms of bipolar I disorder (manic and mixed episodes) in children and teens.