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U.S. FULL PRESCRIBING INFORMATION, including Boxed WARNINGS, and Medication Guide.

Antidepressants may increase suicidal thoughts or behaviors in some children, teenagers, and young adults, especially within the first few months of treatment or when the dose is changed. Depression and other serious mental illnesses are themselves associated with an increase in the risk of suicide. Patients on antidepressants and their families or caregivers should watch for new or worsening depression symptoms, unusual changes in behavior, or thoughts of suicide. Such symptoms should be reported to the patient's healthcare provider right away, especially if they are severe or occur suddenly. ABILIFY®(aripiprazole) is not approved for use in pediatric patients with depression. See More Safety Information

INDICATION: ABILIFY (aripiprazole) is indicated for the treatment of irritability associated with autistic disorder in pediatric patients 6 to 17 years of age, as part of a total treatment plan.

About Irritability Associated With Autistic Disorder

A child with autistic disorder may already have problems with communication and social interaction. Irritability adds another layer that can cause issues at home, with family, and at school.

Irritability may cause your child to throw temper tantrums, harm himself or herself, become aggressive, or experience other symptoms, such as:

  • Inappropriate screaming or yelling
  • Depressed mood
  • Quickly changing mood
  • Demanding behavior
  • Crying in response to apparently minor annoyances
About Irritability From Autism


While there isn’t a cure for irritability associated with autistic disorder, certain behavioral therapies and medications can help improve irritability. Together, they could play an important part in your child’s total treatment plan.

Important Safety Information About Allergic Reactions: Patients should not use ABILIFY (aripiprazole) if they are allergic to aripiprazole or any of the ingredients in ABILIFY. Allergic reactions have ranged from rash, hives and itching to anaphylaxis, which may include difficulty breathing, tightness in the chest, and swelling of the mouth, face, lips, or tongue.

See More Safety Information
  • About ABILIFY

    If your child has been prescribed ABILIFY (aripiprazole), or you wish to discuss it with his or her healthcare professional, it may be helpful to know more about how ABILIFY fits into your child's treatment plan.